Fibroblast Growth Factor Receptor Substrate 2

Preferred Label : Fibroblast Growth Factor Receptor Substrate 2;

NCIt synonyms : SNT-1; FRS2-Alpha; FRS2A; FRS2; SUC1-Associated Neurotrophic Factor Target; FGFR Signaling Adaptor; FGFR-Signaling Adaptor SNT; FGFR Signalling Adaptor; Suc1-Associated Neurotrophic Factor Target 1; FGFR Substrate 2;

NCIt definition : Fibroblast growth factor receptor substrate 2 (508 aa, 57 kDa) is encoded by the human FRS2 gene. This protein plays a role in the propagation of signals from fibroblast growth factor receptors and nerve growth factor receptors to their downstream signaling proteins.;

Details

Origin ID

C29587;

UMLS CUI

C0540129;

OMIM relation
- Fibroblast growth factor receptor substrate 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- FRS2 protein, human [MeSH concept]
- FRS2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- FRS2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- PTB Domain [NCIt concept]
gene_product_is_element_in_pathway
- FGF Signaling Pathway [NCIt concept]
- Neurotrophic Factor-Mediated NTRK1 Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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