NCIt definition : The maleate salt form of fluvoxamine, a 2-aminoethyl oxime ether of aralkylketones,
with antidepressant, antiobsessive-compulsive, and antibulimic activities. Fluvoxamine
blocks serotonin reuptake by inhibiting the serotonin reuptake pump of the presynaptic
neuronal membrane leading to an increase of serotonin levels within the synaptic cleft.
This results in facilitated serotonergic transmission and decreased serotonin turnover
leading to antidepressant and antiobsessive-compulsive effects.;
Alternative definition : NCI-GLOSS: A drug used to treat obsessive-compulsive disorder. It is a type of antidepressant
agent and selective serotonin reuptake inhibitor (SSRI).;