Fluvoxamine - CISMeF

Preferred Label : Fluvoxamine;

NCIt definition : A 2-aminoethyl oxime ether of aralkylketones, with antidepressant, antiobsessive-compulsive, and anxiolytic properties. Fluvoxamine, chemically unrelated to other selective serotonin reuptake inhibitors, selectively blocks serotonin reuptake by inhibiting the serotonin reuptake pump at the presynaptic neuronal membrane. This increases serotonin levels within the synaptic cleft, prolongs serotonergic transmission and decreased serotonin turnover, thereby leading to antidepressant, anxiolytic and antiobsessive-compulsive effects. Fluvoxamine shows no significant affinity for histaminergic, alpha or beta adrenergic, muscarinic, or dopaminergic receptors in vitro.;

Alternative definition : NCI-GLOSS: A drug used to treat obsessive-compulsive disorder. It is a type of antidepressant agent and selective serotonin reuptake inhibitor (SSRI).;

UNII : O4L1XPO44W;

InChIKey : CJOFXWAVKWHTFT-XSFVSMFZSA-N;

CAS number : 54739-18-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 54739-18-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C15H21F3N2O2;

ChEBI ID : CHEBI:5138;

Codes from synonyms : CDR0000450109;

Details

Origin ID

C61769;

UMLS CUI

C0085228;

Automatic exact mappings (from CISMeF team)
- Fluvoxamine [ICHI extension code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fluvoxamine [ICD-11 Extension code]
- Fluvoxamine (substance) [SNOMED CT concept]
- Product containing fluvoxamine (medicinal product) [SNOMED CT concept]
- fluvoxaMINE [LOINC component]
- fluvoxamine [ATC Code]
- fluvoxamine [Substance BNPC]
- fluvoxamine [MeSH concept]
- fluvoxamine [MeSH Descriptor]
- fluvoxamine [SNOMED Notion]
Validated automatic mappings to BTNT
- fluvoxamine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_salt_form
- Fluvoxamine Maleate [NCIt concept]
is_free_acid_or_base_form_of
- Fluvoxamine Maleate [NCIt concept]

Keyword's position in hierarchy(ies) :

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