" /> Clozapine - CISMeF





Preferred Label : Clozapine;

NCIt synonyms : 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine;

NCIt definition : A synthetic dibenzo-diazepine derivative, atypical antipsychotic Clozapine blocks several neurotransmitter receptors in the brain (dopamine type 4, serotonin type 2, norepinephrine, acetylcholine, and histamine receptors). Unlike traditional antipsychotic agents, it weakly blocks dopamine type 2 receptors. It relieves schizophrenic symptoms (hallucinations, delusions, dementia). (NCI04);

UNII : J60AR2IKIC;

InChIKey : QZUDBNBUXVUHMW-UHFFFAOYSA-N;

CAS number : 5786-21-0;

Chemical formula : C18H19ClN4;

ChEBI ID : CHEBI:3766;

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31/07/2025


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