Preferred Label : Clozapine;
NCIt synonyms : 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine;
NCIt definition : A synthetic dibenzo-diazepine derivative, atypical antipsychotic Clozapine blocks
several neurotransmitter receptors in the brain (dopamine type 4, serotonin type 2,
norepinephrine, acetylcholine, and histamine receptors). Unlike traditional antipsychotic
agents, it weakly blocks dopamine type 2 receptors. It relieves schizophrenic symptoms
(hallucinations, delusions, dementia). (NCI04);
UNII : J60AR2IKIC;
InChIKey : QZUDBNBUXVUHMW-UHFFFAOYSA-N;
CAS number : 5786-21-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 5786-21-0
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G-SRS /a ;
Chemical formula : C18H19ClN4;
ChEBI ID : CHEBI:3766;
Origin ID : C28936;
UMLS CUI : C0009079;
- Semantic type(s)
- UMLS correspondences (same concept)
- clozapine [International Nonproprietary Name]
- chemical_or_drug_is_metabolized_by_enzyme
- concept_is_in_subset