C-X-C Motif Chemokine 10

Preferred Label : C-X-C Motif Chemokine 10;

NCIt synonyms : Interferon-Inducible Cytokine IP-10; IFN-Gamma-Inducible Protein-10; C-X-C Motif Chemokine Ligand 10; Interferon-alpha Inducible Protein 10; Chemokine (C-X-C Motif) Ligand 10; Interferon-Gamma-Induced Factor; Gamma IP10; CXCL10; IP10; IP-10; Interferon-Gamma Induced Protein; Small Inducible Cytokine-B10; Small Inducible Cytokine B10; Interferon-Gamma-Inducible Protein 10; Interferon Gamma-Induced Factor; Gamma-IP10; 10 kDa Interferon Gamma-Induced Protein; Small-Inducible Cytokine B10;

NCIt definition : C-X-C motif chemokine 10 (98 aa, 11 kDa) is encoded by the human CXCL10 gene. This protein is involved in chemotaxis of monocytes and T-lymphocytes.;

NCIt note : C-X-C motif chemokine 10 is cleaved C-terminally to form CXCL10(1-73). This processed form inhibits chemotaxis.;

Details

Origin ID

C28756;

UMLS CUI

C1308752;

OMIM relation
- Chemokine, cxc motif, ligand 10 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CXCL10 protein, human [MeSH concept]
- CXCL10 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CXC Cytokine Gene [NCIt concept]
- CXCL10 Gene [NCIt concept]
- Cytokine Gene [NCIt concept]
gene_product_has_associated_anatomy
- Central Nervous System [NCIt concept]
- Epithelial Cell [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_is_element_in_pathway
- CXCR3-Mediated Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cellular Migration Process [NCIt concept]
- Chemotactic Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immune Response Process [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Maturation [NCIt concept]
- NK Cell Activation [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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