TFIIA-Alpha and Beta Like Factor

Preferred Label : TFIIA-Alpha and Beta Like Factor;

NCIt synonyms : GTF2A1-Like Factor; General Transcription Factor II A 1-Like Factor; ALF; General Transcription Factor II A, 1-Like Factor; TFIIA-Alpha/Beta-Like Factor; TFIIA Large Subunit Isoform ALF; TFIIA-Alpha-Beta-Like Factor; GTF2A1L;

NCIt definition : TFIIA-alpha and beta-like factor (478 aa, 52 kDa) is encoded by the human GTF2A1L gene. This protein may be involved in the regulation of transcription in the testes.;

NCIt note : TFIIA-Alpha/Beta-Like Factor is a testis-specific general transcription factor with conserved regions I and IV and acidic region III, but a distinct region II. With GTF2A2 and TBP, ALF binds DNA and allows mRNA transcription initiation. ALF may be functionally identical with GTF2A1.;

Details

Origin ID

C28701;

UMLS CUI

C1431931;

OMIM relation
- General transcription factor iia, 1-like [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GTF2A1L protein, human [MeSH concept]
- GTF2A1L protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Basal Transcription Factor Gene [NCIt concept]
- GTF2A1L Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Testis [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcription Initiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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