Mothers Against Decapentaplegic Homolog 6

Preferred Label : Mothers Against Decapentaplegic Homolog 6;

NCIt synonyms : hSMAD6; Mothers Against Decapentaplegic Homolog 6 Protein; MAD, Mothers Against Decapentaplegic Homolog 6 Protein; Mothers Against DPP Homolog 6 Protein; SMAD6; Mothers Against Decapentaplegic, Drosophila, Homolog 6 Protein; SMA- and MAD-Related Protein 6; MADH6; SMAD Family Member 6; SMAD6 Protein; SMAD 6; MAD Homolog 6;

NCIt definition : Mothers against decapentaplegic homolog 6 (496 aa, 53 kDa) is encoded by the human SMAD6 gene. This protein is involved in receptor signaling-dependent regulation of gene transcription.;

Details

Origin ID

C26481;

UMLS CUI

C0540682;

Currated CISMeF NLP mapping
- Smad6 protein [MeSH concept]
- smad6 protein [MeSH Descriptor]
OMIM relation
- Smad family member 6 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SMAD6 protein, human [MeSH concept]
- SMAD6 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- SMAD6 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- ALK Pathway [NCIt concept]
- BMP Receptor Signaling Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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