Epiregulin - CISMeF

Preferred Label : Epiregulin;

NCIt synonyms : EREG;

NCIt definition : Epiregulin (49 aa, 6 kDa) is encoded by the human EREG gene. This protein is involved in the positive regulation of cell proliferation.; Epiregulin (49 aa, 6 kDa) is encoded by the human EREG gene. This protein is involved in the positive regulation of cell proliferation.;

NCIt note : The active form of the growth factor, epiregulin, is produced by two proteolytic cleavage events that remove 59 N-terminal amino acids and 61 amino acids from the C-terminus of proepiregulin. The precursor is a type I membrane protein and the mature form is a secreted protein. (UniProt);

Détails

Origin ID

C26171;

UMLS CUI

C3884279;

Automatic exact mappings (from CISMeF team)
- Epiregulin [MeSH Descriptor]
- Epiregulin [MeSH concept]
- Epiregulin [OMIM gene]
- epiregulin [HGNC gene]
OMIM relation
- Epiregulin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- EREG protein, human [MeSH concept]
- EREG protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- EREG Gene [NCIt concept]
- Growth Factor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Growth Factor [NCIt concept]
gene_product_has_structural_domain_or_motif
- EGF-Like Domain [NCIt concept]
gene_product_is_element_in_pathway
- ERBB Family Signaling Pathway [NCIt concept]
- ERBB4 Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Family Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients