" /> Donepezil Hydrochloride - CISMeF





Preferred Label : Donepezil Hydrochloride;

NCIt synonyms : 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine Hydrochloride; Donepezil;

NCIt definition : The hydrochloride salt of a piperidine derivative with neurocognitive-enhancing activity. Donepezil reversibly inhibits acetylcholinesterase, thereby blocking the hydrolysis of the neurotransmitter acetylcholine and, consequently, increasing its activity. This agent may improve neurocognitive function in Alzheimer's disease, reduce sedation associated with opioid treatment of cancer pain, and improve neurocognitive function in patients who have received radiation therapy for primary brain tumors or brain metastases.;

UNII : 3O2T2PJ89D;

InChIKey : XWAIAVWHZJNZQQ-UHFFFAOYSA-N;

CAS number : 120011-70-3; 142057-77-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 120011-70-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 142057-77-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Aricept;

Molecule name : E-2020;

Chemical formula : C24H29NO3.HCl;

ChEBI ID : CHEBI:4696;

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14/05/2024


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