RAS Family Gene

Preferred Label : RAS Family Gene;

NCIt related terms : ras gene family;

NCIt definition : A family of genes that encode structurally similar small GTPases involved in a variety of signal transduction pathways. Mutation of genes in this family is associated with cancer.;

Alternative definition : NCI-GLOSS: A family of genes that may cause cancer when they are mutated (changed). They make proteins that are involved in cell signaling pathways, cell growth, and apoptosis (cell death). Agents that block the actions of a mutated ras gene or its protein may stop the growth of cancer. Members of the ras gene family include Kras, Hras, and Nras.;

Codes from synonyms : CDR0000045859;

Details

Origin ID

C25784;

UMLS CUI

C1335597;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GTPase HRas [NCIt concept]
- GTPase KRas [NCIt concept]
- GTPase Nras [NCIt concept]
- p21 RAS Protein [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Signal Transduction [NCIt concept]
genetic_biomarker_related_to
- RAS Wild Type [NCIt concept]
- RAS/BRAF/NF1 Triple Wild Type [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients