Preferred Label : Iodine I 131 Tositumomab;

NCIt synonyms : Iodine-131 Tositumomab; 131-I-Anti-B1 Monoclonal Antibody; I 131 Tositumomab; Iodine-131 Anti-CD20 Monoclonal Antibody; Iodine I 131 MOAB Anti-B1; I 131 Monoclonal Antibody Anti-B1; Iodine-131 Anti-B1 Antibody; Iodine I 131 Monoclonal Antibody Anti-B1; I131-MOAB-B1;

NCIt related terms : TOSITUMOMAB I-131; Tositumomab and I-131 (Bexxar); Tositumomab and I-131;

NCIt definition : A monoclonal antibody directed against the CD20 protein expressed on the surface of B-lymphocytes and radiolabeled with the radioisotope iodine I 131 with potential antineoplastic activity. Iodine I 131 tositumomab binds to and selectively delivers cyctotoxic radiation to CD20-expressing B-lymphocytes, thereby minimizing systemic radiotoxicity.;

Alternative definition : NCI-GLOSS: A monoclonal antibody (tositumomab) that has been chemically changed by adding radioactive iodine, and that is used in the treatment of certain types of non-Hodgkin lymphoma. It belongs to the family of drugs called radioconjugated monoclonal antibodies. When iodine I 131 tositumomab and tositumomab are given together, the combination is called the Bexxar regimen.;

UNII : K1KT5M40JC;

CAS number : 192391-48-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 192391-48-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Bexxar;

NSC code : 715813;

Codes from synonyms : CDR0000367409; 506; 11194;

Details


Keyword's position in hierarchy(ies) : arborescence

Main resources

You can consult :


https://pgtmsite.files.wordpress.com/2024/01/ibritumomab_tositumomab_pgtm_20060209.pdf
2006
Canada
drug information
Tositumomab and Iodine I 131 Tositumomab
Iodine I 131 Tositumomab
Tositumomab
lymphoma, Non-Hodgkin
Iodine I 131 Tositumomab

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12/05/2024


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