Amoxicillin - CISMeF

Preferred Label : Amoxicillin;

NCIt synonyms : AMOX; Amoxicillin Trihydrate;

NCIt related terms : Amoxil;

NCIt definition : A broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity. Amoxicillin binds to and inactivates penicillin-binding protein (PBP) 1A located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.;

Alternative definition : NCI-GLOSS: A drug used to treat some bacterial infections. Amoxicillin is a form of penicillin that is made in the laboratory. It kills certain types of bacteria. It is a type of antibiotic.;

UNII : 804826J2HU;

InChIKey : MQXQVCLAUDMCEF-CWLIKTDRSA-N;

CAS number : 61336-70-7;

Drug name : Polymox; Wymox; Utimox; Trimox; Amoxil;

Chemical formula : C16H19N3O5S.3H2O;

NSC code : 277174;

ChEBI ID : CHEBI:51254;

Codes from synonyms : CDR0000045451; NSC0277174; 11533;

Details

Origin ID

C237;

UMLS CUI

C0002645;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Amoxicillin [ICD-11 Extension code]
- Amoxicillin [LOINC component]
- Amoxicillin (substance) [SNOMED CT concept]
- Product containing amoxicillin (medicinal product) [SNOMED CT concept]
- amoxicillin [ATC Code]
- amoxicillin [Substance BNPC]
- amoxicillin [MeSH concept]
- amoxicillin [MeSH Descriptor]
- amoxicillin [SNOMED Notion]
Validated automatic mappings to BTNT
- Amoxicillin trihydrate [SMS substance]
- Amoxicillin trihydrate (substance) [SNOMED CT concept]
- amoxicillin [ATC Code]
- amoxicillin trihydrate [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Amoxicillin Sodium [NCIt concept]
is_component_of_chemotherapy_regimen
- Amoxicillin/Clarithromycin/Omeprazole [NCIt concept]
is_free_acid_or_base_form_of
- Amoxicillin Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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