NCIt definition : The sodium salt form of a broad-spectrum, semisynthetic aminopenicillin antibiotic
with bactericidal activity. Amoxicillin binds to and inactivates penicillin-binding
proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation
of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial
cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and
results in the weakening of the bacterial cell wall and causes cell lysis.;