Amoxicillin Anhydrous

Preferred Label : Amoxicillin Anhydrous;

NCIt synonyms : Amoxicilline; (2S,5R,6R)-6-((R)-(-)-2-Amino-2-(P-Hydroxyphenyl)Acetamido)-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo(3.2.0)Heptane-2-Carboxylic Acid; 4-Thia-1-Azabicyclo(3.2.0)Heptane-2-Carboxylic Acid, 6-((Amino(4-Hydroxyphenyl)Acetyl)Amino)-3,3-Dimethyl-7-Oxo-(2S-(2Alpha,5Alpha,6Beta(S*)))-;

NCIt definition : The anhydrous form of a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity. Amoxicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.;

UNII : 9EM05410Q9;

InChIKey : LSQZJLSUYDQPKJ-NJBDSQKTSA-N;

CAS number : 26787-78-0;

Chemical formula : C16H19N3O5S;

ChEBI ID : CHEBI:2676;

Détails

Origin ID

C87367;

UMLS CUI

C2828282;

Automatic exact mappings (from CISMeF team)
- Amoxicillin [LOINC component]
- Amoxicillin [ICHI extension code]
- Amoxicillin (substance) [SNOMED CT concept]
- Product containing amoxicillin (medicinal product) [SNOMED CT concept]
- amoxicillin [MeSH Descriptor]
- amoxicillin [Substance BNPC]
- amoxicillin [MeSH concept]
- amoxicillin [ATC Code]
- amoxicillin [SNOMED Notion]
CISMeF manual mappings
- amoxicillin anhydrous [MeSH concept]
See also inter- (CISMeF)
- Product containing amoxicillin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Amoxicillin anhydrous (substance) [SNOMED CT concept]
- amoxicillin anhydrous [MeSH concept]
Validated automatic mappings to NTBT
- Amoxicillin [LOINC component]
- Amoxicillin [ICD-11 Extension code]
- Amoxicillin [SMS substance]
- Amoxicillin (substance) [SNOMED CT concept]
- amoxicillin [MeSH Descriptor]
- amoxicillin [Substance BNPC]
- amoxicillin [MeSH concept]
- amoxicillin [SNOMED Notion]
- amoxicillin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

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