DNA Mismatch Repair Protein Mlh3

Preferred Label : DNA Mismatch Repair Protein Mlh3;

NCIt synonyms : MutL Protein Homolog 3; MLH3; DNA Mismatch Repair Protein-MLH3;

NCIt definition : DNA mismatch repair protein Mlh3 (1453 aa, 164 kDa) is encoded by the human MLH3 gene. This protein is involved in DNA mismatch repair.;

NCIt note : MLH3 interacts with MLH1 and shares the same MLH-interacting region with PMS1 and PMS2. The balance of these three competing MLH1 partners might be important in DNA mismatch repair.;

Details

Origin ID

C21465;

UMLS CUI

C1333233;

OMIM relation
- Dna mismatch repair protein mlh3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- DNA mismatch repair protein Mlh3 [LOINC component]
- MLH3 protein, human [MeSH concept]
- MLH3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- MLH3 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Mismatch Repair Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Mismatch Repair Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Lynch Syndrome [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- Mismatch Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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