Adenomatous Polyposis Coli Protein 2

Preferred Label : Adenomatous Polyposis Coli Protein 2;

NCIt synonyms : APCL; APC2; Adenomatous Polyposis Coli Like Protein; APC-Like; Adenomatous Polyposis Coli Protein-Like;

NCIt definition : Adenomatous polyposis coli protein 2 (2303 aa, 244 kDa) is encoded by the human APC2 gene. This protein is involved in the regulation of catenin beta-1 turnover.;

Details

Origin ID

C21324;

UMLS CUI

C1431561;

OMIM relation
- Apc2 regulator of wnt signaling pathway 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- APC2 protein, human [MeSH Supplementary Concept]
- APC2 protein, human [MeSH concept]
gene_encodes_gene_product
- APC2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Actin Filament [NCIt concept]
- Microtubule [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Basal Cell Carcinoma Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_malfunction_associated_with_disease
- Familial Adenomatous Polyposis [NCIt concept]
gene_product_plays_role_in_biological_process
- Signal Transduction [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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