THAP Domain-Containing Protein 1

Preferred Label : THAP Domain-Containing Protein 1;

NCIt synonyms : THAP1; THAP Domain Protein 1; THAP Domain Containing Protein 1;

NCIt definition : THAP domain-containing protein 1 (213 aa, 25 kDa) is encoded by the human THAP1 gene. This protein plays a role in transcription factor and pro-apoptotic activities.;

NCIt note : THAP domain-containing protein 1 binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence. (UniProt);

Details

Origin ID

C213069;

OMIM relation
- Thap domain-containing protein 1 [OMIM gene]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- THAP1 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- Zinc-Binding, DNA-Binding Motif [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients