Drug Tolerance

Preferred Label : Drug Tolerance;

NCIt synonyms : Tolerance;

NCIt definition : A reduction in the sensitivity to a drug following its repeated administration, in which increased doses are required to produce the same magnitude of effect previously produced by a smaller dose. This increase in dose may be necessitated by changes in the metabolism of the drug, or a cellular, physiological or behavioral adaptation to the effects of the drug.;

Alternative definition : NCI-GLOSS: A condition that occurs when the body gets used to a medicine so that either more medicine is needed or different medicine is needed.;

Codes from synonyms : CDR0000044739;

Details

Origin ID

C21130;

UMLS CUI

C0013220;

Currated CISMeF NLP mapping
- Drug tolerance [MedDRA Preferred Term]
- TOLERANCE [WHO-ART Preferred Term]
- Tolerance, function (observable entity) [SNOMED CT concept]
- drug tolerance [MeSH Descriptor]
- drug tolerance [MeSH concept]
- drug tolerance, nos [SNOMED Notion]
- self tolerance [MeSH Descriptor]
- tolerance, nos [SNOMED Notion]
False automatic mappings
- Drug tolerance (disorder) [SNOMED CT concept]
- Drug tolerance (observable entity) [SNOMED CT concept]
- graft rejection [Disease (Nov.)]
Semantic type(s)
- Finding [UMLS semantic type]
UMLS correspondences (same concept)
- Drug tolerance [MedDRA Preferred Term]
- Drug tolerance (disorder) [SNOMED CT concept]
- Drug tolerance (observable entity) [SNOMED CT concept]
- drug tolerance [MeSH concept]
- drug tolerance [MeSH Descriptor]
- drug tolerance, nos [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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