drug tolerance

Preferred Label : drug tolerance;

MeSH definition : Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.;

MeSH synonym : tolerance, drug; drug tolerances; tolerances, drug;

MeSH annotation : differentiate from DRUG RESISTANCE; not for tolerability ( drug /adv eff): Manual 28.19;

Wikipedia link : https://en.wikipedia.org/wiki/Drug tolerance;

Details

Origin ID

D004361;

UMLS CUI

C0013220;

Allowable qualifiers
- ethnology [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Currated CISMeF NLP mapping
- Drug Tolerance [NCIt concept]
- Drug tolerance [MedDRA Preferred Term]
- Drug tolerance (disorder) [SNOMED CT concept]
- drug tolerance, nos [SNOMED Notion]
Ne pas confondre avec
- drug resistance [MeSH Descriptor]
Record concept(s)
- drug tolerance [MeSH concept]
Semantic type(s)
- Finding [UMLS semantic type]
UMLS correspondences (same concept)
- Drug Tolerance [NCIt concept]
- Drug tolerance [MedDRA Preferred Term]
- Drug tolerance (disorder) [SNOMED CT concept]
- Drug tolerance (observable entity) [SNOMED CT concept]
- drug tolerance, nos [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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