ETS-Related Transcription Factor Elf-3

Preferred Label : ETS-Related Transcription Factor Elf-3;

NCIt synonyms : E74-Like Factor 3 ETS Domain Transcription Factor; ELF3 Protein; ELF3; Epithelial-Restricted With Serine Box; Epithelium-Specific Ets Transcription Factor 1; ETS Domain Transcription Factor, Epithelial-Specific; Epithelium-Specific ETS Factor 1; E74-Like Factor 3; Epithelium-Restricted Ets Protein ESX; ESE1; ESE-1; ESX Protein; E74-Like Factor-3;

NCIt definition : ETS-related transcription factor Elf-3 (371 aa, 41 kDa) is encoded by the human ELF3 gene. This protein plays a role in the positive regulation of transcription.;

NCIt note : ESX, a novel member of the ETS transcription factor family, is a tumor marker exclusively expressed in epithelial cells. ESX contains two putative DNA-binding domains: an ETS domain and an A/T hook domain.;

Details

Origin ID

C20900;

UMLS CUI

C1308058;

OMIM relation
- E74-like ets transcription factor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ELF3 protein, human [MeSH concept]
- ELF3 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- ELF3 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Epithelial Cell [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- ETS Family Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- ETS Domain [NCIt concept]
gene_product_is_biomarker_of
- Malignant Ovarian Neoplasm [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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