Fms-Related Tyrosine Kinase 3 Ligand

Preferred Label : Fms-Related Tyrosine Kinase 3 Ligand;

NCIt synonyms : FMS-Related Tyrosine Kinase-3 Ligand; FLT 3 Ligand; FLT3LG; SL Cytokine; FLT3 Ligand; FLT3-L;

NCIt definition : Fms-related tyrosine kinase 3 ligand (235 aa, 26 kDa) is encoded by the human FLT3LG gene. This protein is involved in the positive regulation of hematopoietic cell proliferation.;

Details

Origin ID

C20492;

UMLS CUI

C1442820;

OMIM relation
- Fms-related tyrosine kinase 3 ligand [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- FLT3LG Gene [NCIt concept]
- Hematopoietic Factor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Bone Marrow [NCIt concept]
- Cytoplasm [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Growth Factor [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
is_target
- CDK2/4/6/FLT3 Inhibitor FN-1501 [NCIt concept]

Keyword's position in hierarchy(ies) :

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