" /> Betacellulin - CISMeF





Preferred Label : Betacellulin;

NCIt synonyms : Beta-Cellulin; Beta Cellulin; BTC;

NCIt definition : Betacellulin (80 aa, 9 kDa) is encoded by the human BTC gene. This protein is involved in epidermal growth factor receptor family signaling pathways.;

NCIt note : The active form of the growth factor, called betacellulin, is produced by proteolytic cleavage that removes 67 amino acids from the C-terminus of probetacellulin. The precursor is a type I membrane protein and the mature form is a secreted protein. (UniProt); Betacellulin is a member of the EGF family of growth factors and a potent mitogen for retinal pigment epithelia and vascular smooth muscle cells. Betacellulin effects are mediated by the EGF receptor and related receptors. (UniProt);

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31/07/2025


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