Pyrin - CISMeF

Preferred Label : Pyrin;

NCIt synonyms : Marenostrin; MEFV;

NCIt definition : Pyrin (781 aa, 86 kDa) is encoded by the human MEFV gene. This protein plays a role in inflammasome formation and autophagy.;

NCI Metathesaurus CUI : CL599809;

Details

Origin ID

C203788;

UMLS CUI

C4308322;

OMIM relation
- Mefv innate immunity regulator, pyrin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MEFV protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Immunoprotein Gene [NCIt concept]
- MEFV Gene [NCIt concept]
gene_product_has_associated_anatomy
- Autophagosome [NCIt concept]
- Cytoplasm [NCIt concept]
- Microtubule [NCIt concept]
- Nucleoplasm [NCIt concept]
gene_product_has_structural_domain_or_motif
- Metal Binding Site [NCIt concept]
- Nuclear Localization Signal [NCIt concept]
gene_product_is_element_in_pathway
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Autophagy [NCIt concept]
- Immune System Process [NCIt concept]
- Inflammatory Response [NCIt concept]

Keyword's position in hierarchy(ies) :

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