Licensing Factor

Preferred Label : Licensing Factor;

NCIt definition : S-phase onset is controlled, so that it occurs only once every cell cycle. DNA is licensed for replication after mitosis in G(1), and passage through S-phase removes the license to replicate. Licensing factors are required for licensing and central to ensuring that replication occurs once per cell cycle. (from J Biol Chem 2001 Nov 30;276(48):44905-11);

Details

Origin ID

C20319;

UMLS CUI

C1334394;

Biochemical function of gene products
- DNA Replication Factor Cdt1 [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Cell Cycle Gene [NCIt concept]
- Licensing Factor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- Regulatory Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Replication Initiation [NCIt concept]
- Replication Licensing [NCIt concept]

Keyword's position in hierarchy(ies) :

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