N-Myristoylation

Preferred Label : N-Myristoylation;

NCIt definition : N-Myristoylation is the covalent attachment of myristic acid, a saturated 14-carbon fatty acid inserted in the cytoplasmic leaflet of the lipid bilayer, by an amide linkage to the amino-terminal glycine residue of a protein in order to increase the hydrophobicity of some membrane proteins or to promote membrane localization of some cytoplasmic proteins.;

Details

Origin ID

C19420;

UMLS CUI

C1513807;

Semantic type(s)
- Molecular Function [UMLS semantic type]
biological_process_involves_gene_product
- Glycylpeptide N-Tetradecanoyltransferase 1 [NCIt concept]
- Glycylpeptide N-Tetradecanoyltransferase 2 [NCIt concept]
biological_process_is_part_of_process
- Biochemical Process [NCIt concept]
- Membrane Protein Traffic [NCIt concept]
- Post-Translational Regulation [NCIt concept]
process_involves_gene
- NMT1 Gene [NCIt concept]
- NMT1 wt Allele [NCIt concept]
- NMT2 Gene [NCIt concept]
- NMT2 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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