NMT2 wt Allele

Preferred Label : NMT2 wt Allele;

NCIt synonyms : N-Myristoyltransferase 2 wt Allele;

NCIt definition : Human NMT2 wild-type allele is located within 10p13 and is approximately 61 kb in length. This allele, which encodes glycylpeptide N-tetradecanoyltransferase 2 protein, plays a role in the N-terminal myristoylation of many signaling proteins. The NMT gene is overexpressed in several types of cancer including brain, colorectal and gall bladder tumors.;

NCIt note : N-terminal myristoylation of proteins plays a putative role in carcinogenesis. Since NMT2 gene expression is induced by dioxin, this gene may be involved in the mechanism of dioxin carcinogenicity.;

GenBank Accession Number : NM_004808;

Details

Origin ID

C51049;

UMLS CUI

C1709132;

OMIM relation
- N-myristoyltransferase 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 10p13 [NCIt concept]
gene_plays_role_in_process
- N-Myristoylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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