Heterotrimeric G Protein Subunit

Preferred Label : Heterotrimeric G Protein Subunit;

NCIt definition : The alpha, beta, and gamma subunits (or beta-gamma dimers) of heterotrimeric guanine nucleotide binding (G) proteins are intracellular membrane-associated proteins activated by various receptors (e.g., beta adrenergic). They serve as transducers of the receptor-initiated response linked to intracellular elements, such as enzymes, that generate second messengers to initiate an effect. These proteins have a high affinity for guanine nucleotides and hence are named G proteins.;

Details

Origin ID

C19273;

UMLS CUI

C1333999;

Biochemical function of gene products
- G Beta-Gamma [NCIt concept]
- G(i) Alpha [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Signaling Pathway Gene [NCIt concept]
gene_product_is_physical_part_of
- Heterotrimeric G Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Environment-to-Cell Communication [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- GTP Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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