Ephrin Receptor

Preferred Label : Ephrin Receptor;

NCIt synonyms : EPH;

NCIt definition : Eph receptor tyrosine kinases and their ligands, the ephrins, appear to lie functionally at the interface between pattern formation and morphogenesis. They play a major role in axonal pathfinding and target recognition during central nervous system (CNS) development. (from Development 1999;126:2033-2044 and Exp Neurol 1999;156:218-22);

NCIt note : The signaling pathways downstream of ephrin receptors are referred to as forward signaling while the signaling pathways downstream of the ephrin ligands are referred to as reverse signaling. (UniProt);

Details

Origin ID

C18606;

UMLS CUI

C0908506;

Biochemical function of gene products
- Ephrin Type-B Receptor 1 [NCIt concept]
- Ephrin Type-B Receptor 2 [NCIt concept]
- Ephrin Type-B Receptor 3 [NCIt concept]
- Ephrin Type-B Receptor 4 [NCIt concept]
- Ephrin Type-B Receptor 6 [NCIt concept]
Currated CISMeF NLP mapping
- receptors, eph family [MeSH concept]
- receptors, eph family [MeSH Descriptor]
False automatic mappings
- Hereditary elliptocytosis [ORDO Disease]
- hepatic encephalopathy [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- receptors, eph family [MeSH Descriptor]
- receptors, eph family [MeSH concept]
Validated automatic mappings to BTNT
- ephrin A receptors [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Receptor Tyrosine Kinase [NCIt concept]
gene_product_plays_role_in_biological_process
- Receptor Signaling [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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