Neurogenic Differentiation Factor 2

Preferred Label : Neurogenic Differentiation Factor 2;

NCIt synonyms : Class A Basic Helix-Loop-Helix Protein 1; bHLHa1; NeuroD-Related Factor 2; NeuroD2; NDRF;

NCIt definition : Neurogenic differentiation factor 2 (382 aa, 41 kDa) is encoded by the human NEUROD2 gene. This protein plays a role in neuronal differentiation and maintenance.;

NCIt note : Neurogenic differentiation factor 2 binds to E box-containing sequences 5'-CANNTG-3', which are usually found in neuron-specific promoters. (EntrezGene and UniProt);

Details

Origin ID

C185604;

UMLS CUI

C1452453;

Automatic exact mappings (from CISMeF team)
- neuronal differentiation 2 [ORDO Gene]
OMIM relation
- Neurogenic differentiation 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NEUROD2 protein, human [MeSH Supplementary Concept]
- NEUROD2 protein, human [MeSH concept]
gene_encodes_gene_product
- NEUROD2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- BHLH Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Neural Development [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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