Myc-Associated Zinc Finger Protein

Preferred Label : Myc-Associated Zinc Finger Protein;

NCIt synonyms : Pur-1; Purine-Binding Transcription Factor; Transcription Factor Zif87; MYC Associated Zinc Finger Protein; Serum Amyloid A-Activating Factor-1; SAF-1; Zinc Finger Protein 801; MAZI; MAZ; ZF87;

NCIt definition : Myc-associated zinc finger protein (477 aa, 49 kDa) is encoded by the human MAZ gene. This protein plays a role in transcriptional activation and sequence-specific binding to gene promoters.;

NCIt note : At least 4 isoforms have been documented for Myc-associated zinc finger protein, which are products of alternative splicing. Isoform 2 may act as a dominant negative when bound to isoform 1. (UniProt);

Détails

Origin ID

C185013;

UMLS CUI

C1449203;

Automatic exact mappings (from CISMeF team)
- MYC associated zinc finger protein [HGNC gene]
- Myc-associated zinc finger protein [OMIM gene]
- purine rich element binding protein A [ORDO Gene]
OMIM relation
- Myc-associated zinc finger protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MAZ protein, human [MeSH concept]
gene_encodes_gene_product
- MAZ Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcription Termination [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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