RGS Family Protein

Preferred Label : RGS Family Protein;

NCIt synonyms : RGS Protein; Regulator of G-Protein Signaling Family Protein;

NCIt definition : RGS family proteins activate GTPase and regulate G protein signaling by stimulating the inactivation of heterotrimeric G proteins. RGS family proteins are responsible for the rapid turnoff of G protein-coupled receptor signaling pathways. There are indications that a subset of RGS proteins regulate specific G protein-coupled receptor pathways.;

Details

Origin ID

C18166;

UMLS CUI

C0633372;

Currated CISMeF NLP mapping
- RGS proteins [MeSH Descriptor]
- RGS proteins [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RGS proteins [MeSH concept]
- RGS proteins [MeSH Descriptor]
gene_encodes_gene_product
- RGS Family Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- RGS Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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