MeSH definition : A large family of evolutionarily conserved proteins that function as negative regulators
of HETEROTRIMERIC GTP-BINDING PROTEINS. RGS PROTEINS act by increasing the GTPase
activity of the G alpha subunit of a heterotrimeric GTP-binding protein, causing it
to revert to its inactive (GDP-bound) form.;
MeSH synonym : rgs protein (g-protein signaling); regulators of g-protein signaling proteins; regulators of g protein signaling proteins;
MeSH annotation : do not confuse with GTP-BINDING PROTEIN REGULATORS; not the same as RGS tripeptide;
A large family of evolutionarily conserved proteins that function as negative regulators
of HETEROTRIMERIC GTP-BINDING PROTEINS. RGS PROTEINS act by increasing the GTPase
activity of the G alpha subunit of a heterotrimeric GTP-binding protein, causing it
to revert to its inactive (GDP-bound) form.