Transcription Factor MafG

Preferred Label : Transcription Factor MafG;

NCIt synonyms : MAFG; Small MAF Protein G; MAFG Protein; hMAF; v-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog G;

NCIt definition : Transcription factor MafG (162 aa, 18 kDa) is encoded by the human MAFG gene. This protein plays a role in the regulation of globin gene expression.;

NCIt note : Globin gene expression is regulated through NFE2 elements upstream of alpha- and beta-gene clusters. NFE2 DNA-binding involves a heterodimer containing a ubiquitous small MAF protein (MAFF, MAFG, or MAFK) and tissue-specific p45 NFE2.;

Details

Origin ID

C18047;

UMLS CUI

C0534921;

Currated CISMeF NLP mapping
- MafG transcription factor [MeSH concept]
- mafg transcription factor [MeSH Descriptor]
OMIM relation
- Maf bzip transcription factor g [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MAFG protein, human [MeSH Supplementary Concept]
- MAFG protein, human [MeSH concept]
- MafG transcription factor [MeSH concept]
- mafg transcription factor [MeSH Descriptor]
gene_encodes_gene_product
- MAFG Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- MAF Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- bZIP Domain [NCIt concept]
gene_product_is_element_in_pathway
- Oxidative Stress Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients