Preferred Label : Gunagratinib;
NCIt synonyms : Pan-FGFR Inhibitor ICP-192;
NCIt definition : A small molecule pan inhibitor of human fibroblast growth factor receptors (FGFRs),
with potential antiangiogenic and antineoplastic activities. Upon oral administration,gunagratinib
inhibits the activities of FGFRs, which may result in the inhibition of both tumor
angiogenesis and tumor cell proliferation, and the induction of tumor cell death.
FGFRs, a family of receptor tyrosine kinases upregulated in various tumor cell types,
may be involved in tumor cell differentiation and proliferation, tumor angiogenesis,
and tumor cell survival.;
UNII : 9D589FD91A;
CAS number : 2211082-53-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2211082-53-8
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Molecule name : ICP-192; ICP 192;
NCI Metathesaurus CUI : CL1647816;
Origin ID : C178318;
UMLS CUI : C5667216;
Semantic type(s)
- concept_is_in_subset
- has_target
