" /> Positive Transcription Elongation Factor B - CISMeF





Preferred Label : Positive Transcription Elongation Factor B;

NCIt synonyms : P-TEFb;

NCIt definition : A cyclin-dependent kinase complex that promotes the release of RNA polymerase II (Pol II) from promoter proximal pausing and leads to transcript elongation and mRNA synthesis. This complex is a heterodimer comprised of the serine-threonine kinase cyclin-dependent kinase 9 and either cyclin-T1, cyclin-T2 or cyclin-K.;

NCI Metathesaurus CUI : CL1647678;

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31/07/2025


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