Casirivimab - CISMeF

Preferred Label : Casirivimab;

NCIt definition : A recombinant, human immunoglobulin G1 (IgG1) kappa monoclonal antibody directed against the spike protein (SP) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), that can potentially be used for immunization against COVID-19. Upon administration, casirivimab specifically targets and binds to the receptor-binding domain (RBD) of SP, thereby blocking viral attachment and entry into human cells and may thereby neutralize SARS-CoV-2. This may slow the progression of the disease and accelerate recovery, and may potentially provide temporary protection against infection with SARS-CoV-2.;

UNII : J0FI6WE1QN;

CAS number : 2415933-42-3;

Molecule name : REGN 10933; REGN-10933;

NCI Metathesaurus CUI : CL1642809;

Details

Origin ID

C177087;

UMLS CUI

C5422688;

CISMeF manual mappings
- casirivimab [MeSH Supplementary Concept]
- casirivimab [MeSH concept]
Currated CISMeF NLP mapping
- Casirivimab (substance) [SNOMED CT concept]
- casirivimab [MeSH concept]
- casirivimab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Casirivimab (substance) [SNOMED CT concept]
- Product containing casirivimab (medicinal product) [SNOMED CT concept]
- casirivimab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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