Etesevimab - CISMeF

Preferred Label : Etesevimab;

NCIt synonyms : Anti-COVID-19 Monoclonal Antibody JS016; Anti-SARS-CoV-2 Monoclonal Antibody JS016; Anti-COVID-19 Spike Protein Monoclonal Antibody JS016;

NCIt related terms : Monoclonal antibodies against SARS-CoV-2: etesevimab;

NCIt definition : An Fc-modified neutralizing, recombinant, human monoclonal antibody directed against the spike (S) protein receptor binding domain (RBD) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), that can potentially be used for immunization against Coronavirus disease 2019 (COVID-19). Upon administration of etesevimab, this agent specifically targets and binds to the RBD of the SARS-CoV-2 S protein. This blocks viral attachment and entry into human host cells and may thereby neutralize SARS-CoV-2. This may slow the progression of the disease and accelerate recovery, and may also provide temporary protection against infection with SARS-CoV-2. S-protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus.;

UNII : N7Q9NLF11I;

CAS number : 2423948-94-9;

Molecule name : JS 016; JS-016;

NCI Metathesaurus CUI : CL1407894;

Origin ID

C173977;

UMLS CUI

C5421804;

CISMeF manual mappings
- etesevimab [MeSH concept]
- etesevimab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- etesevimab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- ACC/AHA COVID-19 Appendix Variables [NCIt concept]
- ACC/AHA Cardiovascular and Noncardiovascular Complications of COVID-19 Terminology [NCIt concept]
- Appendix 8: Pharmacological Therapy Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
- Therapies for COVID-19 Terminology [NCIt concept]

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