Imdevimab - CISMeF

Preferred Label : Imdevimab;

NCIt definition : A recombinant, human immunoglobulin G1 (IgG1) lambda monoclonal antibody directed against the spike protein (SP) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), that can potentially be used for immunization against COVID-19. Upon administration, imdevimab specifically targets and binds to the receptor-binding domain (RBD) of SP, thereby blocking viral attachment and entry into human cells and may thereby neutralize SARS-CoV-2. This may slow the progression of the disease and accelerate recovery, and may potentially provide temporary protection against infection with SARS-CoV-2.;

UNII : 2Z3DQD2JHM;

CAS number : 2415933-40-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2415933-40-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : REGN 10987; REGN-10987;

NCI Metathesaurus CUI : CL1642857;

Details

Origin ID

C177063;

UMLS CUI

C5422689;

CISMeF manual mappings
- imdevimab [MeSH concept]
- imdevimab [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Imdevimab (substance) [SNOMED CT concept]
- imdevimab [MeSH concept]
- imdevimab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Imdevimab (substance) [SNOMED CT concept]
- Product containing imdevimab (medicinal product) [SNOMED CT concept]
- imdevimab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

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