Sotrovimab - CISMeF

Preferred Label : Sotrovimab;

NCIt synonyms : Anti-SARS-CoV-2 Spike Protein Monoclonal Antibody VIR-7831;

NCIt related terms : Monoclonal antibodies against SARS-CoV-2: sotrovimab;

NCIt definition : A neutralizing human monoclonal antibody directed against the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), that can potentially be used for passive immunization against Coronavirus disease 2019 (COVID-19). Upon administration, sotrovimab specifically targets and binds to an epitope on the SARS-CoV-2 S protein that is shared with SARS-CoV-1, thereby blocking viral attachment and entry into human cells and may thereby neutralize SARS-CoV-2. This may slow the progression of the disease and accelerate recovery, and may potentially provide temporary protection against infection with SARS-CoV-2. S protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus.;

UNII : 1MTK0BPN8V;

CAS number : 2423014-07-5;

Molecule name : GSK 4182136; VIR 7831; VIR-7831; GSK-4182136;

NCI Metathesaurus CUI : CL1656267;

Details

Origin ID

C177059;

UMLS CUI

C5433947;

Currated CISMeF NLP mapping
- Sotrovimab [Anticorps monoclonal]
- Sotrovimab [SMS substance]
- Sotrovimab (substance) [SNOMED CT concept]
- VIR-7831 [MeSH concept]
- sotrovimab [MeSH Supplementary Concept]
- sotrovimab [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing sotrovimab (medicinal product) [SNOMED CT concept]
- Sotrovimab (substance) [SNOMED CT concept]
- sotrovimab [MeSH Supplementary Concept]
- sotrovimab [ATC Code]
Validated automatic mappings to BTNT
- sotrovimab [ATC Code]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- ACC/AHA COVID-19 Appendix Variables [NCIt concept]
- ACC/AHA Cardiovascular and Noncardiovascular Complications of COVID-19 Terminology [NCIt concept]
- Appendix 8: Pharmacological Therapy Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
- Therapies for COVID-19 Terminology [NCIt concept]
has_target
- SARS-CoV-2 Spike Glycoprotein [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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