Remdesivir - CISMeF

Preferred Label : Remdesivir;

NCIt synonyms : RDV; 2-Ethylbutyl (2S)-2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; L-Alanine, N-((S)-hydroxyphenoxyphosphinyl)-, 2-Ethylbutyl Ester, 6-Ester with 2-C-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-D-altrononitrile;

NCIt related terms : Veklury; SARS-CoV-2 antiviral agents: remdesivir;

NCIt definition : A prodrug of an adenosine triphosphate (ATP) analog, with potential antiviral activity against a variety of RNA viruses. Upon administration, remdesivir, being a prodrug, is metabolized into its active form GS-441524. As an ATP analog, GS-441524 competes with ATP for incorporation into RNA and inhibits the action of viral RNA-dependent RNA polymerase. This results in the termination of RNA transcription and decreases viral RNA production.;

UNII : 3QKI37EEHE;

InChIKey : RWWYLEGWBNMMLJ-YSOARWBDSA-N;

CAS number : 1809249-37-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1809249-37-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Veklury;

Molecule name : GS-5734;

NCI Metathesaurus CUI : CL553517;

Details

Origin ID

C152185;

UMLS CUI

C4726677;

Automatic exact mappings (from CISMeF team)
- remdesivir [ATC Code]
CISMeF manual mappings
- remdesivir [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Remdesivir (substance) [SNOMED CT concept]
- remdesivir [COVID-19 Thesaurus concept]
- remdesivir [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing remdesivir (medicinal product) [SNOMED CT concept]
- Remdesivir (substance) [SNOMED CT concept]
- remdesivir [MeSH Supplementary Concept]
- remdesivir [ATC Code]
concept_is_in_subset
- ACC/AHA COVID-19 Appendix Variables [NCIt concept]
- ACC/AHA Cardiovascular and Noncardiovascular Complications of COVID-19 Terminology [NCIt concept]
- Appendix 8: Pharmacological Therapy Terminology [NCIt concept]
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
- Therapies for COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients