Zinc Finger Protein Gfi-1

Preferred Label : Zinc Finger Protein Gfi-1;

NCIt synonyms : Growth Factor Independent Protein 1; Zinc Finger Protein 163; Growth Factor Independence-1B Protein; GFI1;

NCIt definition : Zinc finger protein Gfi-1 (422 aa, 45 kDa) is encoded by the human GFI1 gene. This protein is involved in hematopoiesis.;

NCIt note : Zinc finger protein Gfi-1 binds to 5'-TAAATCAC[AT]GCA-3', which is found in the promoter region of target genes. (UniProt);

Details

Origin ID

C176512;

UMLS CUI

C5444811;

OMIM relation
- Growth factor-independent 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- GFI1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Hematopoietic Stem Cell [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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