Linear Ubiquitin Chain Assembly Complex

Preferred Label : Linear Ubiquitin Chain Assembly Complex;

NCIt synonyms : LUBAC;

NCIt definition : A protein complex that forms a heteromultimer and is involved in the conjugation of linear polyubiquitin chains to protein substrates.;

NCIt note : LUBEC is comprised of E3 ubiquitin-protein ligase RNF31, RanBP-type and C3HC4-type zinc finger-containing protein 1 and sharpin. (UniProt);

NCI Metathesaurus CUI : CL1642299;

Details

Origin ID

C176221;

UMLS CUI

C5447111;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Ubiquitin-Activating Enzyme Gene [NCIt concept]
gene_product_has_biochemical_function
- Ligase [NCIt concept]
gene_product_has_chemical_classification
- Protein or Riboprotein Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Ubiquitination [NCIt concept]
has_gene_product_element
- E3 Ubiquitin-Protein Ligase RNF31 [NCIt concept]
- RanBP-Type and C3HC4-Type Zinc Finger-Containing Protein 1 [NCIt concept]
- Sharpin [NCIt concept]

Keyword's position in hierarchy(ies) :

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