CD11 Protein Family

Preferred Label : CD11 Protein Family;

NCIt synonyms : CD11; CD11 Family; CD11 Protein; CD11 Family Protein;

NCIt related terms : CD11 Antigen;

NCIt definition : A family comprised of four integrin alpha subunits that are expressed on the surface of leukocytes and usually form a complex with integrin beta-2 (ITGB2/CD18). CD11/CD18 integrins play a role in leukocyte-endothelial cell adhesion through binding to intercellular adhesive molecule-1 (ICAM-1; CD54) or ICAM-2 (CD102), which are expressed on the surface of endothelial cells.;

NCI Metathesaurus CUI : CL1413012;

Details

Origin ID

C175565;

UMLS CUI

C0054942;

Biochemical function of gene products
- Integrin Alpha-D [NCIt concept]
- Integrin Alpha-L [NCIt concept]
- Integrin Alpha-M [NCIt concept]
- Integrin Alpha-X [NCIt concept]
Currated CISMeF NLP mapping
- CD11 Antigens [MeSH Descriptor]
- CD11 Antigens [MeSH concept]
See also inter- (CISMeF)
- CD11 cells [LOINC component]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- CD11 Antigens [MeSH Descriptor]
- CD11 Antigens [MeSH concept]
gene_product_has_biochemical_function
- Integrin [NCIt concept]

Keyword's position in hierarchy(ies) :

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