Krueppel-Like Factor 2

Preferred Label : Krueppel-Like Factor 2;

NCIt synonyms : KLF2; Kruppel-Like Factor LKLF; Kruppel Like Factor 2; Lung Kruppel-Like Factor; Lung Krueppel-Like Factor; Lung Kruppel-Like Zinc Finger Transcription Factor;

NCIt definition : Krueppel-like factor 2 (355 aa, 37 kDa) is encoded by the human KLF2 gene. This protein is involved in the positive regulation of gene expression.;

NCIt note : Krueppel-like factor 2 binds to the CACCC box of target genes. (UniProt);

Details

Origin ID

C162391;

UMLS CUI

C5202871;

Automatic exact mappings (from CISMeF team)
- KLF transcription factor 2 [HGNC gene]
- Kruppel-like factor 2 [OMIM gene]
OMIM relation
- Kruppel-like factor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- KLF2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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