Preferred Label : mSMILE Regimen;
NCIt synonyms : Modified SMILE; Modified SMILE Regimen; Modified-SMILE; Dexamethasone-Methotrexate-Ifosfamide-Pegaspargase-Etoposide; Dexamethasone/Methotrexate/Ifosfamide/Pegaspargase/Etoposide; mSMILE;
NCIt definition : A modified version of the SMILE regimen consisting of dexamethasone, methotrexate,
ifosfamide, pegaspargase and etoposide that can be used in the treatment of natural
killer (NK)/T-cell lymphoma. Compared to SMILE, in mSMILE the pegylated L-asparaginase
is substituted for L-asparaginase and the regimen cycle length is shortened.;
NCI Metathesaurus CUI : CL937921;
Origin ID : C158387;
UMLS CUI : C4764212;
Semantic type(s)
chemotherapy_regimen_has_component
concept_is_in_subset