GSN wt Allele - CISMeF

Preferred Label : GSN wt Allele;

NCIt synonyms : AGEL; DKFZp313L0718; ADF; Gelsolin wt Allele; Amyloidosis, Finnish Type Gene; Gelsolin (Amyloidosis, Finnish Type) Gene;

NCIt definition : Human GSN wild-type allele is located in the vicinity of 9q33.2 and is approximately 125 kb in length. This allele, which encodes gelsolin protein, plays a role in both assembly and disassembly of actin filaments. Mutation of the gene is associated with Finnish type familial amyloidosis (amyloidosis V).;

NCI Metathesaurus CUI : CL552044;

GenBank Accession Number : X04412;

Details

Origin ID

C150252;

UMLS CUI

C4723849;

Automatic exact mappings (from CISMeF team)
- Destrin [OMIM gene]
- gelsolin [ORDO Gene]
OMIM relation
- Gelsolin [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Caspase Cascade in Apoptosis [NCIt concept]
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
- Extracellular Matrix Binding Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- N-Cadherin Signaling Pathway [NCIt concept]
- Osteopontin-Mediated Signaling Pathway [NCIt concept]
- Rho Cell Motility Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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