EGFR NP_005219.2:p.C797S

Preferred Label : EGFR NP_005219.2:p.C797S;

NCIt synonyms : EGFR C797S; NP_005219.2:p.C797S; Epidermal Growth Factor Receptor C797S; EGFR p.C797S; EGFR Cys797Ser; NP_005219.2:p.Cys797Ser; Proto-Oncogene c-ErbB-1 C797S; Epidermal Growth Factor Receptor Cys797Ser; Receptor Tyrosine-Protein Kinase erbB-1 C797S; EGFR p.Cys797Ser; Proto-Oncogene c-ErbB-1 Cys797Ser; Receptor Tyrosine-Protein Kinase erbB-1 Cys797Ser; EGFR NP_005219.2:p.Cys797Ser;

NCIt definition : A change in the amino acid residue at position 797 in the epidermal growth factor receptor protein where cysteine has been replaced by serine.;

NCIt note : This variation may be associated with development of osimertinib resistance.;

NCI Metathesaurus CUI : CL545043;

Details

Origin ID

C147011;

UMLS CUI

C4687645;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_sequence_variation_encoded_by_gene_mutant
- EGFR Gene Mutation [NCIt concept]
- EGFR NM_005228.3:c.2389T>A [NCIt concept]
- EGFR NM_005228.3:c.2390G>C [NCIt concept]
gene_product_variant_of_gene_product
- Epidermal Growth Factor Receptor [NCIt concept]
is_target
- EGFR Inhibitor WJ13404 [NCIt concept]
- EGFR Mutant-selective Inhibitor BBT-176 [NCIt concept]
- EGFR Mutant-selective Inhibitor BLU-701 [NCIt concept]
- EGFR Mutant-selective Inhibitor BPI-361175 [NCIt concept]
- EGFR Mutant-selective Inhibitor H002 [NCIt concept]
- EGFR Mutant-selective Inhibitor HS-10375 [NCIt concept]
- EGFR Mutant-selective Inhibitor NX-019 [NCIt concept]
- EGFR Mutant-selective Inhibitor QLH11811 [NCIt concept]
- Mutant-selective EGFR Inhibitor JIN-A02 [NCIt concept]
- Mutant-selective EGFR Inhibitor TAS3351 [NCIt concept]
- Tigozertinib [NCIt concept]
molecular_abnormality_involves_gene
- EGFR Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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