RRAGC wt Allele

Preferred Label : RRAGC wt Allele;

NCIt synonyms : GTR2; FLJ13311; TIB929; Ras Related GTP Binding C wt Allele; Ras-Related GTP Binding C Gene; RAGC;

NCIt definition : Human RRAGC wild-type allele is located in the vicinity of 1p34.3 and is approximately 22 kb in length. This allele, which encodes Ras-related GTP-binding protein C, plays a role in regulating the localization of the mammalian target of rapamycin complex 1 (mTORC1).;

NCIt note : Mutation of the RRAGC gene may be associated with diffuse large B-cell lymphoma (DLBCL). (Cell. 2017;171:481-494.e15.);

NCI Metathesaurus CUI : CL540248;

GenBank Accession Number : AF323609;

Details

Origin ID

C142216;

UMLS CUI

C4553357;

Automatic exact mappings (from CISMeF team)
- Ras-related gtp-binding protein C [OMIM gene]
OMIM relation
- Ras-related gtp-binding protein C [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1p34.3 [NCIt concept]
gene_is_element_in_pathway
- Autophagy Regulation Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
gene_plays_role_in_process
- Autophagy [NCIt concept]
- Cellular Stress Response [NCIt concept]
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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