Ubiquitin-Associated and SH3 Domain-Containing Protein A

Preferred Label : Ubiquitin-Associated and SH3 Domain-Containing Protein A;

NCIt synonyms : T-Cell Ubiquitin Ligand 1; STS-2; TULA-1; Suppressor of T-Cell Receptor Signaling; Cbl-Interacting Protein 4; CLIP4; T-Cell Ubiquitin Ligand Protein;

NCIt definition : Ubiquitin-associated and SH3 domain-containing protein A (661 aa, 74 kDa) is encoded by the human UBASH3A gene. This protein may be involved in the inhibition of T-cell receptor signaling.;

NCIt note : Ubiquitin-associated and SH3 domain-containing protein A contains a phosphatase-like domain but this protein possesses negligible phosphatase activity. (J. Cell. Biochem. 2008; 104: 953-964. doi:10.1002/jcb.21678.);

Details

Origin ID

C131173;

UMLS CUI

C0965248;

Automatic exact mappings (from CISMeF team)
- Ubiquitin-associated and sh3 domain-containing protein a [OMIM gene]
- ubiquitin associated and SH3 domain containing A [HGNC gene]
OMIM relation
- Ubiquitin-associated and sh3 domain-containing protein a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- UBASH3A protein, human [MeSH Supplementary Concept]
- UBASH3A protein, human [MeSH concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- UBASH3A Gene [NCIt concept]
gene_product_expressed_in_tissue
- Bone Marrow [NCIt concept]
- Spleen [NCIt concept]
- Thymus Gland [NCIt concept]
gene_product_has_associated_anatomy
- Leukocyte [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH3 Domain [NCIt concept]
- UBA Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Receptor Desensitization [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]

Keyword's position in hierarchy(ies) :

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