Slit Homolog 1 Protein

Preferred Label : Slit Homolog 1 Protein;

NCIt synonyms : Multiple Epidermal Growth Factor-Like Domains Protein 4; Slit Homolog 1; Multiple EGF-Like Domains Protein 4; Slit-1;

NCIt definition : Slit homolog 1 protein (1534 aa, 168 kDa) is encoded by the human SLIT1 gene. This protein plays a role in the development of blood vessels and the differentiation of neurons.;

NCIt note : Slit homolog 1 protein is a ligand for roundabout homolog 1 and can bind to gremlin-1.;

Details

Origin ID

C126784;

UMLS CUI

C1454834;

Automatic exact mappings (from CISMeF team)
- Slit guidance ligand 1 [OMIM gene]
OMIM relation
- Slit guidance ligand 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SLIT1 protein, human [MeSH Supplementary Concept]
- SLIT1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- SLIT1 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Forebrain [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_structural_domain_or_motif
- EGF-Like Domain [NCIt concept]
- Leucine-Rich Repeat [NCIt concept]
gene_product_is_element_in_pathway
- Axon Guidance Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Cellular Migration Process [NCIt concept]
- Nervous System Development [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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